According to the guidance of the World Health Organization's 2010, as defined cryptozoospermia:"A sample with no sperm in preparing fresh but observed in the pellet after centrifugation". That is to say, to concentrate the sample we can observe sperm under the microscope. In practice it corresponds to a concentration below 100.000 sperm per milliliter, which it is well below the reference value established by the WHO, 15 million sperm per milliliter, with a total number of sperm 39 million in the total volume of ejaculated.
Around 30% samples initially classified as azoospérmicas have some sperm after centrifugation, and this completely changes the prognosis. It is therefore very important to make a proper diagnosis. These results must be supplemented by physical examination, so it should be evaluated by the urologist, you can also request hormonal reviews, genetic and echocardiographic, to help find the source of that cryptozoospermia. With the results in hand and you can evaluate different options.
As expected success possibilities, in patients under 37 years, the pregnancy rate after ICSI cycle is around 35%.
It is very important to be aware that the reference values appearing in the WHO manual are not the same as the minimum values necessary to achieve conception. Whenever there is a mobile sperm, and an egg to fertilize, it is possible to get pregnant, although chances are very low.