FISH on sperm

FISH (Fluorescence in situ Hybridization) It is a technique used to analyze sperm chromosomes, allowing study numerical and structural alterations.

These analyzes have revealed that about 6% of patients with normal somatic karyotype consulting for infertility it presents meiotic alterations in their spermatogenic cells. This percentage may be increased to a 17,5% in individuals with severe oligoasthenoteratozoospermia and normozoospermic patients with one or more previous IVF failures, up 27%. These cases can affect the production of gametes with chromosomal abnormalities, at the same time, increases the risk of having children affected.